10/1986 - 05/1992
BASF AG - Head of Laboratory for Subacute, Subchronic, Chronic toxicology and Carcinogenicity in Rodents, Expert for Immunotoxicology, Product Stewardship of Fine Chemicals

06/1992 - 08/1995
Consultant for Environmental and Toxicological Services, Kirchheimbolanden, Germany

09/1995 - 03/2001
BASF AG - Product Stewardship for Agro- and Industrial chemicals, Head of Dog Toxicology,
Head of Reproduction Toxicology, Expert of Immunotoxicology

04/2001 - 12/2001
Knoll GmbH/Abbott GmbH - General and Reproduction Toxicologist

01/2002 - 06/2002
SCC GmbH - Senior Manager Regulatory Affairs

Since 07/2002
Principal of IRSC, International Regulatory & Scientific Consulting, Eisenberg, Germany

• US Society of Toxicology (SOT)
• European Teratology Society (ETS)
• German Society of Immunology (DGfI)
• German Society of Clinical Chemistry (DG KC)

• Subacute up to chronic toxicity studies inclusive ophthalmology
• Carcinogenicity studies
• Developmental neurotoxicity studies (DNT)
• Reproduction toxicity studies including pre-, peri- postnatal development
• Immunotoxicity validation studies
• Kinetics screenings
• Dose escalation

The studies were performed in various strains of rats, mice, rabbits and dogs using different routes of administrations. The compounds comprised industrial chemicals, pesticides, biocides, food/feed additives, cosmetic ingredients, fragrances and flavors, pharmaceuticals and excipients for the purpose of registration, notification, risk assessment, method development and round robin tests.